Efficient transfer of a single copy of the transgene at a single chromosomal site. What are the issues with therapeutic cloning? Transgenic mice were created in what year? Betalactoglobulin is expressed in mammary glands. What are the technical approaches to make GM animals? to make more proteins, a cell will need an increased number of what? ), e) locating and mapping a gene that you want to transfer. if a mutation occurs in the regulatory sequence of a gene, what types of issues might arise? c) help determine the structure of the protein and its function. support your answer (? Upgrade to remove ads. Quizlet will be unavailable from 4-5 PM PT. the fact that a goat can produce human proteins means all of the following EXCEPT what? if someone inherits a protein deficiency, it means that the protein what? The plasmid containing the human gene is placed back into the bacterium often using heat shock. Animals bred for many generations to generate transgenic animals homozygous for transgene in all cells. These are totipotent and can differentiate into any cell type in the animal. Where are induced pluripotent stem cells derived from? the regulatory region of a gene is required for what? every cell should contain the transgene … The hope is that these transgenic animals will provide the best model yet for studying human disease and possible therapies. Dismiss. In ______ disease, patients have progressive muscle weakness because of the buildup of glycogen, What did scientists decide to use as a vector for making Alpha Glucosidase (GAA), The drug _____ was the drug created for Pompe's diseae and was a transgenic alpha glucosidase, ______ was the name of the guy who made monozyme, ______ is the natural enzyme responsible for killing bacteria and preventing diarrhea, ________ is a potent antidiarrheal elixir, (T/F) Lysozyme is especially concentrated in human breast milk. Credit: Ingrid Moen et alet al., BMC Cancer,12/21 (2012), 1-10. Describe the process of pronuclear microinjection. how many different amino acids are responsible for making up the thousands of different proteins found in a cell? Diagram 144. c) an organism that contains genes from a different species, it causes blood clots that can lead to heart attacks and strokes, all of the following describe antithrombin deficiency EXCEPT, b) an extremely rare disorder affecting fewer than 1 in every 300,000 people. 3. Describe the process of reproductive cloning, 1. c) two codons represent the amino acid "His".

An example of transgenics - environmental protection, Using transgenic technology to develop yorkshire pigs that excrete less phosphate. When using homologous reombination to create a knockout mouse, you replace the gene of interest with _______. Embryos at multicell stage lead to mosaics, Transgene constructs are packaged into retroviral particles used to infect embryos. Non-pluripotent cells, typically an adult somatic cell, by inducing expression of certain genes. How are induced pluripotent stem cells made. Leads to lines in which the genetic alteration is present in all cells. how many nucleotides would code for this gene? What is the disadvantage of embryonic cell transfer? Which receptor subunit stays open longer NR2B or NR2A? translation is a process that occurs in the _ and uses _ to produce _. the antithrombin gene codes for a chain of 432 amino acids. Without certain animals, we would not have certain kinds of medicines, vaccines, etc. ______ receptor was found to have correlation with memory in mice.

Required to guarantee efficient processing of the mRNA. Describe the process of embryonic cell transfer, 1. A transgenic animal is one whose genome has been altered by the transfer of a gene or genes from another species or breed. A special protein (restriction enzyme) is used to cut the plasmid, and the human gene is inserted. Embryonic stem cells (derived from embryos) are grown in culture. Describe molecular cloning (by recombinant DNA technology), Transfer of an entire genome from one individual to create another individual, Genetically altered animals which may have additional DNA sequences (from another species) or may have particular sequences deleted from/inactivated in their genome (knock out animals). Incorporate a stop-codon into the neo so that all further transcription stops, _______ is an enzyme found in bacteriophage, a bacterial virus that contains DNA not found in animals, _____ are short sequences also found in bacteriophage but not animals, _______ will cause _____ sequences to recombine with each other, and eliminate anything in between, Cre recombinase splices two LoxP sequences together, A gene of interest to get knocked out flanked with LoxP. Sympots of ____ deficiency include damage to the lungs. a) the person would digest less lactose than normal, b) it's a protein that helps to prevent blood clots, d) a segment of DNA that encodes at least one protein, in an animal containing a human transgene, _, b) the regulatory DNA sequence generally comes from the host animal.
Why was transgenic making of AAT in sheep stopped? What are the characteristics of embryonic stem cells? what would most likely happen if a person had one defective allele and the other allele was functional? What are the benefits of retroviral vectors? What happens if you breed from transgenic animals?

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