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Chan, DVM, PhD, "In the past, researchers have used transgenic mouse models to study the disease. (2001) Science 291, 309–312]. Your friend's email. For more than seven decades, the Yerkes National Primate Research Center, Emory University, has been dedicated to conducting essential basic science and translational research to advance scientific understanding and to improve the health and well-being of humans and nonhuman primates.

However, the lack of genetic manipulation seriously restricted the tree shrews as experimental animals, the widespread application and promotion. You can be assured our editors closely monitor every feedback sent and will take appropriate actions. "The development of all such models is invaluable for understanding disease pathogenesis and for developing early diagnostic and treatment strategies," Zola continued. Tree shrews are widely used in scientific experiments, as they’re cheaper to maintain and have a shorter reproduction cycle than other primates. Li Zhaohui is the first author of the paper, Zheng Ping, Zhao Xudong and Yao Yonggang as co-author.
"Access to Emory's department of human genetics, our collaborations with the department of neurology, our own imaging center and, of course, our animal colony make Yerkes one of the few places in the world where this type of study can be done," Zola continued. Change ), You are commenting using your Google account.
We do not guarantee individual replies due to extremely high volume of correspondence. Despite looking like rodents, tree shrews are actually primates, as humans are. First Transgenic Animal This article is from the Magazine of the Society for Science and the Public. Click to email this to a friend (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on Facebook (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on WhatsApp (Opens in new window), Click to share on Skype (Opens in new window). Researchers develop first transgenic nonhuman primate model of Huntington's disease. It was hoped that this would aid research into human diseases that cannot be studied in mice, for example Huntington's disease , strokes , [29] [30] Alzheimer's disease and schizophrenia . The genetically modified rhesus monkey carries the gene encoding green fluorescent protein and was the result of some 224 eggs that were genetically modified and then fertilized to produce 40 embryos and five pregnancies, which resulted in three live births. A. cultivating 40-generation tree shrew spermatogonial stem cell lines; B. stably expressing green fluorescent protein (GFP) Of transgenic tree shrews.

These models do not completely parallel the brain changes and behavioral features observed in humans with HD, thus making the development of a transgenic nonhuman primate model critical to currently treating and ultimately preventing the disease.". Phys.org internet news portal provides the latest news on science, Tech Xplore covers the latest engineering, electronics and technology advances, Science X Network offers the most comprehensive sci-tech news coverage on the web. Sorry, your blog cannot share posts by email.

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